[Answered]: You receive a prescription at the pharmacy for Boric…

You receive a prescription at the pharmacy for Boric Acid 600 mg Vaginal Suppositories in Hydrogenated Vegetable The directions are to insert one suppository per vaginally every night at bedtime for 14 days for yeat infection The quantity dispensed is 14 Your pharmacy stocks Polybase, Fattibase and Witepsol. Your suppository molds have been precalibrated to contain 2.2 g of Polybase, 1.82 g of Fattibase and 1.87 g Witepsol respectively. The density factor for Boric Acid in Cocoa butter is listed in your “practical guide” reference. You can calculate the density factor of Boric Acid in the bases we will use in our lab using the following data: progesterone density factors (DF) are: DF = 1 in Polybase, DF = 1.25 in Fattibase, DF = 1.25 in Cocoa butter, DF = 0.85 in Witepsol. Beyond Use Dating for this product should follow current USP <795> Recommendations and the product should be stored in the refrigerator. In addition to the compenents listed in the compounding today formulation for this preparation, you should add silicon dioxide to the component list, 25mg of silicon dioxide NF for each ONE suppository. Calculate for 30% excess for this formulation.