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[Verified Answer]: While on hospital rounds today the physician…

While on hospital rounds today the physician diagnosed Tiago Richards (54 years old; male; 5 feet 5 inches; 66 kg; SCr 2.3) with a prosthetic joint infections and wants to treat him with cefazolin for the next 6 weeks. The physician asks for dosing recommendations. You find the following information about cefazolin. Selected information from Lexicomp regarding cefazolin for prosthetic joint infections Dosing: IV: 2 g every 8hours for 2 to 6 weeks Renal Impairment: Adult Calculated CrCl Recommended Dose CrCl >=50 mL/minute 2 gm IV every 8 hours CrCl 30 to <50 mL/minute 2 gm IV every 12 hours CrCl >10 to 30 mL/minute 1 gm IV every 12 hours CrCl <= 10 mL/minute 1 gm IV every 24 hours Administration: IV Infuse over 30 minutes. Preparation for Administration: Adult Dilute 500 mg vial with 2 ml of SWFI, 1 gm vial with 2.5 ml SWFI, and 2 gm vial with 5 ml SWFI. Cefazolin has a reported displacement volume of 0.3 ml/500 mg. Further dilute for IV administration in 50 to 100 ml of NS. Using the vial size closest to your recommended dose, how many milliliters should be withdrawn from the vial for a single dose? Answer to the tenths place

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