[Solved]: Pharmacokinetics deals with the absorption,…

Pharmacokinetics deals with the absorption, distribution, metabolism, and elimination (ADME) of drugs from the system. In this case study, we will complete a sample ADME calculation on a hypothetical new drug called ‘Vibe’. Vibe follows Lipinski’s rule of 5, which makes Vibe an outstanding candidate for an efficient orally active drug. This means that Vibe is easily absorbed via passive diffusion from the GI tract to the bloodstream. Once in the blood, Vibe does not require a carrier protein to be transported. Vibe is readily metabolized by the liver, and can be eliminated by the kidney. In Medicine, you will come across a variety of different drugs and formulations. It is important to understand their ADME. Given that most drugs are administered orally, we will focus on this route of administration in this case study. First, we will focus on absorption. If a drug is administered I.V., it is