[Solved]: Hemolytic Uremic Syndrome (HUS) case A 9-year-old…

Hemolytic Uremic Syndrome (HUS) case A 9-year-old female from the rural South was admitted to the hospital with vomiting, diarrhea, high fever, and fatigue that has not resolved in the last 2 weeks. She had lost 15 pounds since her symptoms started. Her chief complaint was lower abdominal pain. Physical examination revealed slight pallor and splenomegaly. The admitting diagnosis was gastroenteritis. Physical examination revealed periorbital and peritibial edema. Laboratory data included the following CBC, PT, APTT, and retic count. TEST RESULTS WBC 6.5 x 103/cmm RBC 4.77 x 106/cmm HGB 12.6 gm/dl HCT 36.9% MCV 77.4 fl MCH 26.4 pg MCHC 34.4 gm/dl RDW 15.9 PLT 55 x 103/cmm Differential Segs 28 % Bands 17 % Lymphs 20 % Monos 8 % Eos 25 % Basos 2 % Peripheral blood smear: Marked decreased platelet count, moderate polychromasia and schistocytes. “Corrected” reticulocyte count 2.5 % PT 13.6 sec INR 1.23 APTT 30 sec Question: In few words, Propose a pathophysiologic mechanism of this disease that produced the provided results. ——————————————————————————————————-