Consider the following table from a nested case-control study conducted to identify risk factors for the transmission of HIV to a health care worker after percutaneous exposure to HIV-infected blood (Cardo et al. A case-control study of HIV seroconversion in health care workers after percutaneous exposure. N Engl J Med 1997; 337:1485-1490). Risk Factor Number of Case Patients % of Case Patients with Risk Factor Number of Control Patients % Control Patients with Risk Factor Visible blood on device 32 84 632 35 What conclusions can you draw about “Visible blood on device” as the potential risk factor for HIV transmission to a health care worker after percutaneous exposure to HIV-infected blood? Justify your conclusion with the odds ratio calculation and interpretation. This nested case-control study was conducted in a fixed cohort where controls were selected at concurrently when a case occurred and any loss to follow-up was not related to the exposure. Name the measure of association calculated in a cohort study that the odds ratio you calculated above is equivalent to?
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[Solved]: Consider the following table from a nested…