[Verified Answer]: A34-year-old man was scheduled to undergo…

A34-year-old man was scheduled to undergo open repair of multiple fractures in one hand. The anesthetic management was brachial plexus anesthesia with bupivacaine. During the injection of the anesthetic the patient suddenly exhibited nystagmus, slurred speech, tremors, muscle twitching, followed by tonic-clonic convulsions. Which of the following statements best explain the neurophysiologic mechanism of the excitatory state Induced by the drug in this patient? A. The drug caused cardiotoxic effects which in turn trigge red the CNS excitation. B. The drug mediated an allergic reaction in a sensitized patient. C. The drug inhibited glutamate reuptake into glutamatergic neurons. D. The drug activated the mesolimbic pathway in the CNS.