A 48-year-old woman is complaining of episodic headaches, palpitations, sweating, and nausea of 3-month duration. Physical examination revealed normal blood pressure with no other significant findings. Serum biochemistry findings include: sodium: 143 mEq/L (135-145 mEq/L), potassium: 4.3 mEq/L (3.6-5.2 mEq/L), TSH: 3.4 μIU/L (0.5-5.0 μIU/L), free T4: 1.4 ng/dL (0.7-1.9 ng/dl), serum cortisol (8 AM): 18 μg/dL (5-23 μg/dL), bicarbonate: 24 mEq/L (22-26 mEq/L), and blood glucose: 5.5 mmol/L (4-6 mmol/L). The patient’s 24-hour ambulatory blood pressure monitoring revealed wild fluctuations in blood pressure with episodes of hypertension. If you are to investigate her further using standard protocols and speculate, what would be the best diagnosis based on the provided justification? a. Licorice ingestion if her plasma aldosterone is low while her plasma renin activity is increased b. Pheochromocytoma if her 24-hour urinary metanephrines are increased. c. Cushing syndrome if both her plasma aldosterone and renin activity are increased d. Reninoma if both her plasma aldosterone and renin activity are decreased. e. Cushing syndrome if her plasma cortisol levels suppress to both low and high dexamethasone.
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[Solved]: A 48-year-old woman is complaining of episodic…