[Expert Solution]: 37-year-old Esther presented to her General…

37-year-old Esther presented to her General Practitioner (GP) after experiencing two-months of spontaneous bruising to her body without any known injuries, bleeding gums, persistent fatigue, and a sore throat. Esther was a recent first-time mother (9-month-old) and thought that these changes were considered normal. Her GP arranged pathology to take a peripheral full blood count (FBC) which showed the following: Haemoglobin: 75g/L (ref. range 120 – 150g/L) WCC: 14 (x 10/L) (ref. range 3.5 – 11 (x10/L)) Neutrophils: 0.8 (x 10/L) (ref. range 1.7 – 7.0 (x10/L)) Platelets: 32 mcL (ref. range 150 – 450 (x10/L)) Blasts %: 50% (ref. range <5%) On receipt of the results, the general practitioner rang the haematologist on call at the local healthcare facility. Esther was contacted and told to attend the emergency department for further testing. On arrival to department Esther was met by the haematologist who took her straight to the oncology ward. A physical examination was undertaken, and the haematologist told Esther that her presentation indicated Acute Myeloid Leukaemia (AML). A bone marrow biopsy was arranged for the next day with the blood smear from this showing 80% blasts cells in the bone marrow; a diagnosis of AML was confirmed. Esther had a Hickman’s line (Central Venous Access Device- refer to image) placed in their chest, was provided with blood cell support (PRBC’s and platelets) and was to begin a high dose chemotherapy induction (7-3 : Cytarabine and DAUNOrubicin) two days following her initial presentation to her GP. On day +6 of Esther's treatment her blood results that morning showed: Haemoglobin: 72g/L (ref. range 120 - 150g/L) Neutrophils: 0.00 (x 10L) (ref. range 1.7 - 7.0 (x10/L)) Platelets: <5 mcL (ref. range 150 - 450 (x10/L)) At 0800 hours, Esther rang the call bell complaining of a sore mouth and difficulty swallowing due to pain. On observation her mouth was filled with new ulcers, her gums were bleeding and mouth and lips were dry indicating severe oral mucositis (refer to image). Esther was provided with mouth care and a stat dose of oral morphine (ordine) 2mg was given. At handover that same morning, Esther is observed to be diaphoretic with increased work of breathing (WOB), rigoring and pale in appearance. Her observations are as follows: Heart rate 125bpm Blood pressure 103/80mmHg Respiratory rate 25/m Temperature 39.3 SaO2 94% Accurately completes the ABCDE frameworks for patients. B. Demonstrates a comprehensive and detailed understanding of the links between the ABCDE assessment findings and underlying pathophysiology. Justifies why the chosen patient requires prioritisation of care.