[Verified Answer]: Given that malnutrition may be present…

Given that malnutrition may be present across the disease course in Alzheimer’s disease (AD), identify 3 major considerations in designing a study to test whether vitamin D supplementation is associated with slowing the progression from mild cognitive impairment to dementia in AD. (Hint: think about study design, who you would enroll, measures you would include and frequency of data collection). Briefly explain each consideration.