a.An epileptic patient w ho has not responded to phenytoin after 2 weeks on 300 mg/day is observed to have a plasma concentration of 4 mg/mL. ● b.Twenty days after the daily dose is subsequently increased to 500 mg, the patients develops signs of toxicity, nystagmus, and ataxia; the plasma concentration of phenytoin is now 36 mg/mL. ● c.Why should only a 67% increase in daily dose give rise to a nine-fold increase in plasma concentrations?
[Answered]: a.An epileptic patient w ho has not responded to…
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