[Answered]: While on hospital rounds today the physician…

While on hospital rounds today the physician diagnosed Mr. Grady Fitzgerald (54 years old; 6 feet 1 inches; 80 kg; SCr 3) with H.flu meningitis. The guidelines recommend treatment with ampicillin and ceftriaxone for this patient. The physician has asked you for dosing recommendations for ampicillin. Answer the following questions as it relates to ampicillin: Selected information from Lexicomp regarding ampicillin for H.flu meningitis Dosing: IV: 2 g every 4 hours for 7 to 21 days Renal Impairment: Adult Calculated CrCl Recommended Dose CrCl >50 mL/minute Administer every 4 hours. CrCl >10 to <=50 mL/minute Administer every 6 hours. CrCl < 10 mL/minute Administer every 8 hours Administration: IV Infuse over 15 minutes. Preparation for Administration: Adult IV: Reconstitute contents of a 2 g vial in 7.4 ml of SWFI. Ampicillin is reported to have a displacement value of 0.2 mL/250 mg. Concentration after dilution should not exceed 30 mg/ml due to concentration- dependent stability restrictions. Usual dilution: 500 mg/50 mL NS; 1 g/50 mL NS; 2 g/100 mL NS. How many milliliters of medication do you need for a single dose?