[Expert Solution]: A patient with thrombocytopenia is suspected…

A patient with thrombocytopenia is suspected of having an inhibitor. Mixing Studies are performed on a patient and the results are below. Reference Ranges (RR) are listed in parentheses following the test result. • PT: 11.1 sec (RR = 10-13sec) • INR: 1.01 • APTT: 84 sec (RR = 23-32sec) • DRVVT: 84 sec (RR = 23-32sec) • 1:1 84 sec • 1:2 70 sec • 1:4 70 sec • 1:8 68 sec • 1:16 66 sec • NPP Control: 27 sec (acceptable control range = 22-32 sec) • Modified Mixing study with addition of phospholipid: 30 sec. A. Based on the test results, the mixing study pattern is consistent with a/an [ Select] [“Inhibitor”, “Deficiency”, “Cannot be determined”] B. Based on the entire panel of test results and the clinical findings, this suggests the patient has a/an [ Select] [“Factor inhibitor”, “Lupus anticoagulant”, “Factor deficiency”] C. The appropriate follow up to these results is [ Select] [“Factor assay”, “Repeat control and rerun the mixing study”, “Nothing further is required”]